Hif bnip3
Web2 de set. de 2024 · 3.3. HIF-1α/BNIP3 Pathway Was Activated during Luteolysis. Previous studies have revealed that hypoxia is involved in the apoptosis of luteal cells in vitro [], implying that HIF-1α may participate in apoptosis during luteal regression in vivo.Thus, we detected the expression changes of HIF-1α signaling and then found an obvious …
Hif bnip3
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Web15 de out. de 2024 · Bellot, G. et al. Hypoxia-induced autophagy is mediated through HIF-induction of BNIP3 and BNIP3L via their BH3 domains. Mol. Cell Biol. 29, 2570–2581 (2009). http://www.aquaticjournal.com/article/doi/10.7541/2024.2024.261
Web1 de dez. de 2024 · By contrast, the excitomotor of HIF-1α significantly increased BNIP3 expression under OGD/R injury, which was correlated with HIF-1α expression. … WebAB - Mesquita et al. show that genetic deficiency of HIF-1α in the myeloid compartment promotes de novo lipogenesis through the BNIP3/mTOR/SREBP-1c axis. This is …
Web3 de set. de 2024 · Highlights Baicalin mitigates H9c2 cell viability loss and apoptosis aroused by hypoxia; Baicalin activates HIF1a/BNIP3 pathway in hypoxia-exposed H9c2 cells; Silencing HIF1α weakens the influences of baicalin on hypoxia-exposed H9c2 cells; Baicalin promotes Nrf2/HO-1 pathway in hypoxia-exposed H9c2 cells; Web27 de jul. de 2024 · (Bnip3) was substantially upregulated in the inner retinal layer after retinal I/R. In this regard, we further examined Bnip3 depletion in retinal neurons in vitro …
Web27 de dez. de 2024 · HIF-1 α exerts its antiapoptotic function through transcriptional activation of antiapoptotic proteins: Bcl-2, apoptosis inhibitor (IAP-2), and GLUT1. On the other hand, a functional pathway of HIF-1 α can activate proapoptotic proteins: p53, Bax, and BNIP3 [ 5 ].
Web2、n autophagy mediated by HIF-1/BNIP3 and missed abortion By:Yinfang Wang Supervisor:Enwu Yuan Clinical Laboratory Diagnostics The Third Affiliated Hospital of Zhengzhou University May2024 原创性声明原创性声明 秉承郑州大学严谨的学风与优良的科学道德，本人郑重声明：所呈交的学 位论文，是本人在导师的指导下，进行研究所取得 … biologically orientedWebIn contrast, adenovirus-mediated BNIP3 overexpression significantly reversed the decreased mitophagy, and prevented enhanced kidney damage in tubular HIF-1α … daily medication for panic attacksWebUnder normoxia, HIF-1 alpha undergoes hydroxylation at specific prolyl residues which leads to an immediate ubiquitination and subsequent proteasomal degradation of the subunit. In contrast, under hypoxia, HIF … biologically oriented psychologistWeb1 de set. de 2001 · To additionally check the role of Hif-1α in BNIP3 induction, CHO KA13 and C4.5 cells were subjected to normoxia or hypoxia for 16 h before being analyzed … biologically or geneticallyWebAlternatively, a variety of mitophagy receptors, including BNIP3L, BNIP3, FUNDC1 ... Greenberg AH, Harris AL. HIF-1-dependent regulation of hypoxic induction of the cell … daily medication organizer and benefitsWebHIF-1 and HIF-2 appear to be evenly matched in their capacity to induce BNIP3-dependent autophagy. In agreement with these studies, HIF-1-dependent expression of BNIP3 was described to be essential in mitochondrial autophagy (also called mitophagy), as described in MEFs (Zhang et al., 2008) and later in mole rat heart tissue (Band et al., 2009). daily medication for ocular migrainesWeb17 de mai. de 2024 · BNIP3 depletion halted mitophagy and enforced a PHD2-mediated downregulation of HIF-1α and its glycolytic program both in vitro and in vivo. … daily medication log chart