Dynamo mapping vector field of single cells
WebFeb 17, 2024 · In this work, we introduced dynamical systems theory and differential geometry analyses to single-cell genomics. A dynamical system describes the time …
Dynamo mapping vector field of single cells
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WebSingle-cell (sc)-RNA-seq, together with RNA-velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, … WebQiu X, Zhang Y, Yang D, et al. Mapping vector field of single cells[J]. Biorxiv, 2024. 这个 RNA velocity and beyond 系列之后大概会写 Theory 部分 ，主要介绍 model detail，怎么 estimate parameter等，最后写 beyond 的部分，也就是dynamo 的内容。 欢迎大家在评论区讨论（虽然我估计没什么人看hhhh）
WebFeb 1, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these … WebJul 9, 2024 · The reconstructed vector field further enables global mapping of potential landscapes that reflects the relative stability of a given cell state, and the minimal …
WebJul 9, 2024 · Here, we introduce dynamo , an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity vector fields that predict future cell fates, and finally employs differential geometry analyses to elucidate the underlying regulatory networks. WebFeb 1, 2024 · The researchers confirmed dynamo 's cell fate predictions by testing it against cloned cells-cells that share the same genetics and ancestry. One of two nearly-identical clones would be sequenced ...
WebFeb 17, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting …
WebSingle-cell RNA-seq pseudotime estimation algorithms. Single cells, many algorithms. The goal of this page is to catalog the many algorithms that estimate pseudotimes for cells based on their gene expression levels. This problem is also referred to as single-cell trajectory inference or ordering. reagan\\u0027s raidersWebDynamo. : Mapping Vector Field of Single Cells. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these … how to talk about giving in churchWebFeb 1, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, howev how to talk about fostering a pet in japaneseWebJul 9, 2024 · Abstract. Single-cell RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however ... how to talk about future goals in sopWebFeb 1, 2024 · Dynamo is a computational framework for gaining insights into dynamic biological processes, such as human hematopoiesis, from time-resolved single-cell RNA-seq data. Dynamo constructs … how to talk about paintingsWebDynamo: Mapping Vector Field of Single Cells¶ Understanding how gene expression in single cells progress over time is vital for revealing the mechanisms governing cell fate … reagan\\u0027s pancake house pigeon forge menuWebFeb 2, 2024 · Our analytical framework, dynamo, consists of four integral stages: 1) estimation of genome-wide kinetic rate constants and velocity vectors, 2) reconstruction of single-cell vector field functions with the resultant cell state and velocity samples, 3) in-depth analyses leveraging various differential geometry analyses, and 4) predictions of ... how to talk about money in spanish