Cthrc1 gene

WebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene … WebOct 8, 2012 · Generation of Cthrc1 null mice. (A) Cthrc1 gene targeting schematic showing replacement of exons 2-4 with a PGK-neo cassette. (B) Embryonic stem cell targeting with Southern blot analysis of ...

CTHRC1 expression is a novel shared diagnostic and prognostic biomarker ...

WebDec 22, 2024 · The X-axis represent ligand and receptor pairs, with the first gene expressed on F13-Act-CTHRC1 cells and second gene expressed on the interacting cell types denoted in the Y-axis. Red: upregulated gene in tumor bulk RNA-seq. Blue: downregulated in tumor bulk (none present). WebSep 25, 2024 · Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Circ … how digital music changed the industry https://caraibesmarket.com

Parallel single-cell and bulk transcriptome analyses reveal key ...

WebJul 29, 2013 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted glycoprotein that activates the planar cell polarity pathway of Wnt signaling. Using microarray analysis, we found that the CTHRC1 gene is overexpressed in hepatocellular carcinoma (HCC). The level of CTHRC1 mRNA was measured in 201 surgically resected … http://www.informatics.jax.org/marker/MGI:1915838 WebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to ... how many syns in a warburtons thin bagel

Frontiers Application Potential of CTHRC1 as a Diagnostic and ...

Category:The Role of CTHRC1 in Regulation of Multiple Signaling and ... - Hindawi

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Cthrc1 gene

Dynamic Evolution of the Cthrc1 Genes, a Newly Defined Collagen …

WebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … WebWe recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. Cthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence consistent with the presence of Cthrc1 in the ...

Cthrc1 gene

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WebApr 21, 2024 · One subpopulation, characterized by expression of Cthrc1 (collagen triple helix repeat containing 1), emerges in fibrotic lungs and expresses the highest levels of collagens. ... Gene expression ... WebMar 20, 2024 · The collagen triple helix repeat containing 1 (CTHRC1) gene is located on human chromosome 8q22.3 and was initially identified in balloon injury and normal rat …

Web屈振杰 ,崔 琴. 内蒙古包钢医院1.肿瘤内科;2.消化内科,内蒙古 包头 014010. 胃癌是消化道常见的恶性肿瘤,其发病率及死亡率居恶性肿瘤第2位[1]。 WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt …

WebTreatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease Author links open overlay panel Zhaolian Bian a 1 , Qi Miao a 1 , Wei Zhong a 1 , Haiyan Zhang a , Qixia Wang a , Yanshen Peng a , Xiaoyu Chen a , Canjie Guo a , Li Shen a , Fan Yang a , Jie Xu a , Dekai Qiu a ... WebAug 30, 2024 · Gene ID: 68588, updated on 30-Aug-2024. Summary Other designations. collagen triple helix repeat-containing protein 1. GeneRIFs: Gene References Into …

WebCTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, mutation of the gene has been associated with carcinogenesis in a variety of cell and tissues, most notably esophageal adenocarcinoma and Barrett ...

WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer perspective. In this study, … how digital technology change society in jobWebMay 13, 2024 · A Relative mRNA level of CTHRC1 in primary CRC with metastasis (Mets) and primary CRC without (w/o) Mets using three … how digital transforming medicineWebJun 15, 2024 · Gene expression of Cthrc1 was significantly increased from day 3, peaked at day 5, and fell back at day10 after injury (Fig. 1a). To verify this result, we examined the … how many syns in a snickersWebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics … how dilated should i be at 39 weeksWebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … how dilated for water to breakWebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its … how many syns in belvita biscuitsWebOct 6, 2024 · According to the previous reports, the collagen triple helix repeat containing 1 (CTHRC1) causes tumorigenesis by modulating the tumor microenvironment, however, the evidence is limited to a few human cancer subtypes. ... (GEO) based datasets. During the analysis, we simply queue the CTHRC1 gene in these databases to acquire the KM … how many syns in batchelors savoury rice