Ctcf ctcfl

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August undefined, 2024

WebDec 8, 2024 · The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis. Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation. CTCF and BORIS cooperate with additional Testis-specific transcriptional regulators to regulate gene expression in developing male gametes. CCCTC-binding factor (CTCF), an 11-zinc finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. Transcriptional repressor CTCFL (this protein) is a paralog of CTCF … See more Transcriptional repressor CTCFL also known as BORIS (Brother of Regulator of Imprinted Sites) is a protein that in humans is encoded by the CTCFL gene. See more • Klenova EM, Morse HC, Ohlsson R, Lobanenkov VV (2003). "The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer". Semin. … See more • FactorBook CTCFL • Human CTCFL genome location and CTCFL gene details page in the UCSC Genome Browser. See more

TTCF - What does TTCF stand for? The Free Dictionary

WebSep 3, 2024 · The putative ORFs of these shark CTCFL genes, as well as their CTCF genes (Supplementary Data 1), were all revealed to possess eleven zing finger domains, as known for CTCF and CTCFL genes of ... WebAcronym Definition; FFCF: Fédération des Festivals de Chanson Francophone (French: Federation of Francophone Song Festivals) FFCF: Festival Franco-Coréen du Film … describe a historical site / place in vietnam

Anti-CTCFL Antibodies Invitrogen - Thermo Fisher Scientific

WebCTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes. CTCFL is normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. WebJun 22, 2024 · The Ctcf gene has a close paralog known as Boris (Brother Of the Regulator of Imprinted Sites) or Ctcfl (CCCTC-binding factor-like) 26,27 that appeared later in … WebAug 24, 2024 · Because CTCF and CTCFL do not appear to recruit each other , CTCF may maintain chromatin accessibility at tandem CTCF-binding sites, thereby recruiting CTCFL to nearby genes and initiating transcription. In contrast, most gene promoters were highly depleted of nucleosomes, resulting from combinatorial TF binding. In these sites, loss of … describe a historical event in vietnam

Ctcfl CCCTC-binding factor (zinc finger protein)-like [ (house …

Conditional knock out of transcription factor CTCF in …

WebApr 1, 2024 · CTCF and CTCFL contain N-terminal and C-terminal domains and a central 11-zinc finger region. CTCF binds to approximately 80 000 sites on mammalian … WebCTCFL, a testis-specific DNA binding protein containing 11 C2H2-type zinc fingers, belongs to the CTCF zinc-finger protein family. CTCFL is responsible for insulator function, … describe a hungarian horntail chrysler pacifica 0 percent financing

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Ctcf ctcfl

Molecular basis of CTCF binding polarity in genome folding

WebApr 1, 2024 · CTCF and CTCFL contain N-terminal and C-terminal domains and a central 11-zinc finger region. CTCF binds to approximately 80 000 sites on mammalian … WebChIPAb+ CTCF - ChIP Validated Antibody and Primer Set clone 1.2.1.5.4, from mouse; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-1710044 MSDS, related peer-reviewed papers, technical …

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WebNov 15, 2013 · Estrogens play a key role in breast cancer, with 60-70% of the cases expressing estrogen receptors (ERs), which are encoded by the ESR1 gene. CTCFL, a paralogue of the chromatin organizer CTCF, is a potential biomarker of breast cancer, but its expression in this disease is currently controversial. A positive correlation has been … WebCTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes. CTCFL is normally expressed in a mutually exclusive pattern that …

WebJan 5, 2024 · CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional … WebCTCFL paralog; transcriptional repressor CTCF; Background Information: CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers.

WebNov 5, 2024 · The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin 5 , 8 (2012). WebThis also counts for CTCFL which has homology with its ubiquitously expressed paralog CTCF. Based on serious side effects in patients treated with a TCR targeting MAGE-A3 …

WebThe CCCTC-binding factor (CTCF), which anchors DNA loops that organize the genome into structural domains, has a central role in gene control by facilitating or constraining interactions between genes and their regulatory elements 1,2.In cancer cells, the disruption of CTCF binding at specific loci by somatic mutation 3,4 or DNA hypermethylation 5 …

WebMar 29, 2024 · CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms … describe a job with at least 50 wordsWebCTCFL paralog; Gene names. Name. CTCF. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. ... Sumoylated on Lys-74 and Lys-689; sumoylation of CTCF contributes to the repressive function of CTCF on the MYC P2 promoter. By similarity. Keywords. PTM. #Acetylation; #Isopeptide bond; describe a job that you would not like to doWebAug 12, 2024 · BORIS is a transcriptional factor coded by the CTCFL gene, a paralog of CTCF. BORIS shows a very specific expression pattern; for example, it is highly expressed in testicular germ cells, and has ... describe a kind of negative mental stateWebAntibodies that detect CTCF can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ChIP. These antibodies target CTCF in Human, Mouse, Rat, Non-human primate and Equine samples. Our CTCF polyclonal, recombinant monoclonal and monoclonal antibodies are … describe a killer whaleWebFederação Lusa de Cultura Física (Portuguese: Lusa Federation of Physical Culture) FLCF. First-Level Care Facility. FLCF. Family Life Christian Fellowship (various locations) … describe a job you would not like to doWebNov 2, 2024 · CTCFL/BORIS is testis-specific paralogue of CTCF that evolved through duplication of the CTCF gene, likely in fish. It became testis-specific in mammals. CTCFL/BORIS has similar DNA sequence … describe a host-based firewallWebStatistical differences between individual binding categories (CTCFL, CTCF/CTCFL co-bound and CTCF or CTCFL stand-alone sites) and the average CTCF site as reference … describe a leaderless group discussion